410-552-8126   Make a Payment Facebook Google Plus  
Kuo Internal Medicine
 

PATIENT FORMS CONTACT INFO PATIENT PORTAL ? FAQ

Dr Wilbur Kuo

Health Topic: Osteoporosis


by Dr. Wilbur Kuo, MD
March 15, 2016


What medications are used to treat osteoporosis?

oral bisphosphonates
- such as fosamax, actonel, and boniva
- Most are given once a week; boniva is once a month
- Have to take on an empty stomach, first thing in morning, with 8 oz water, and stay upright without eating for 30-60 minutes after
- Can cause stomach inflammation (gastritis)
- Can't use if have chronic kidney disease or esophageal disorders
- Rare risk of jaw necrosis mostly in patients with cancer. Stop medication if you get bone pains

IV bisphosphonates
- such as reclast or IV boniva
- Given if patient can't tolerate pills
- Reclast is given once a year through a 15 minute infusion
- Boniva is every 3 months
- Cannot be given to patients with kidney problems
- can cause flu-like sxs for 1-3 days

miacalcin
- nasal spray
- helps with vertebral fracture pain
- Taken once a day, alternating nostrils every day

forteo
- used for severe osteoporosis: t-score less than -3.5 or t-score less than -2.5 accompanied by fracture
- Given as an injection every day
- Give for 2 years then follow with a bisphosphonate

Prolia or Xgeva
- used in osteoporosis patients with a fracture, people with kidney disease, or in patients intolerant of oral bisphosphonate
- Given as injection every 6 mos
- Watch for signs of infection

Evista, an estrogen receptor modulator
- for postmenopausal women w/no fx, can't tolerate bisphosphonates, and/or have an increased risk of breast ca
- doesn't work as well as fosamax

Hormone replacement therapy
- no longer first line due to risk of breast cancer, stroke, blood clots, and heart disease


More later...

As always, consult your physician before diagnosis yourself or making treatment changes 



Previous

Dr. Wilbur Kuo & Associates Internal Medicine, LLC.
5963 Exchange Drive, Suite 112, Sykesville, MD 21784
410-552-8126 & additional hours upon request
Fax 443-458-7220

Copyright © 2016-2018 All rights reserved. Use of this website constitutes acceptance of our Privacy Policy.